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Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study

BACKGROUND: Graft-derived cell-free DNA (GcfDNA), which is released into the blood stream by necrotic and apoptotic cells, is a promising noninvasive organ integrity biomarker. In liver transplantation (LTx), neither conventional liver function tests (LTFs) nor immunosuppressive drug monitoring are...

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Detalles Bibliográficos
Autores principales: Schütz, Ekkehard, Fischer, Anna, Beck, Julia, Harden, Markus, Koch, Martina, Wuensch, Tilo, Stockmann, Martin, Nashan, Björn, Kollmar, Otto, Matthaei, Johannes, Kanzow, Philipp, Walson, Philip D., Brockmöller, Jürgen, Oellerich, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404754/
https://www.ncbi.nlm.nih.gov/pubmed/28441386
http://dx.doi.org/10.1371/journal.pmed.1002286