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The effects of immune protein CD3ζ development and degeneration of retinal neurons after optic nerve injury

Major histocompatibility complex (MHC) class I molecules and their receptors play fundamental roles in neuronal death during diseases. T-cell receptors (TCR) function as MHCI receptor on T-cells and both MHCI and a key component of TCR, CD3ζ, are expressed by mouse retinal ganglion cells (RGCs) and...

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Detalles Bibliográficos
Autores principales: He, Tao, Mortensen, Xavier, Wang, Ping, Tian, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404868/
https://www.ncbi.nlm.nih.gov/pubmed/28441398
http://dx.doi.org/10.1371/journal.pone.0175522