Apigenin inhibits TNFα/IL-1α-induced CCL2 release through IKBK-epsilon signaling in MDA-MB-231 human breast cancer cells

Mortality associated with breast cancer is attributable to aggressive metastasis, to which TNFα plays a central orchestrating role. TNFα acts on breast tumor TNF receptors evoking the release of chemotactic proteins (e.g. MCP-1/CCL2). These proteins direct inward infiltration/migration of tumor-asso...

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Detalles Bibliográficos
Autores principales: Bauer, David, Redmon, Natalie, Mazzio, Elizabeth, Soliman, Karam F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404872/
https://www.ncbi.nlm.nih.gov/pubmed/28441391
http://dx.doi.org/10.1371/journal.pone.0175558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404872/
https://www.ncbi.nlm.nih.gov/pubmed/28441391
http://dx.doi.org/10.1371/journal.pone.0175558

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