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Apigenin inhibits TNFα/IL-1α-induced CCL2 release through IKBK-epsilon signaling in MDA-MB-231 human breast cancer cells

Mortality associated with breast cancer is attributable to aggressive metastasis, to which TNFα plays a central orchestrating role. TNFα acts on breast tumor TNF receptors evoking the release of chemotactic proteins (e.g. MCP-1/CCL2). These proteins direct inward infiltration/migration of tumor-asso...

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Detalles Bibliográficos
Autores principales:	Bauer, David, Redmon, Natalie, Mazzio, Elizabeth, Soliman, Karam F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404872/ https://www.ncbi.nlm.nih.gov/pubmed/28441391 http://dx.doi.org/10.1371/journal.pone.0175558

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