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Palmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis

SCP1 as a nuclear transcriptional regulator acts globally to silence neuronal genes and to affect the dephosphorylation of RNA Pol ll. However, we report the first finding and description of SCP1 as a plasma membrane-localized protein in various cancer cells using EGFP- or other epitope-fused SCP1....

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Detalles Bibliográficos
Autores principales: Liao, Peng, Wang, Weichao, Li, Yu, Wang, Rui, Jin, Jiali, Pang, Weijuan, Chen, Yunfei, Shen, Mingyue, Wang, Xinbo, Jiang, Dongyang, Pang, Jinjiang, Liu, Mingyao, Lin, Xia, Feng, Xin-Hua, Wang, Ping, Ge, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404917/
https://www.ncbi.nlm.nih.gov/pubmed/28440748
http://dx.doi.org/10.7554/eLife.22058