Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications

The nicotinic acetylcholine receptor (nAChR) is a major target of autoantibodies in myasthenia gravis (MG), an autoimmune disease that causes neuromuscular transmission dysfunction. Despite decades of research, the molecular mechanisms underlying MG have not been fully elucidated. Here, we present t...

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Detalles Bibliográficos
Autores principales: Noridomi, Kaori, Watanabe, Go, Hansen, Melissa N, Han, Gye Won, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404922/
https://www.ncbi.nlm.nih.gov/pubmed/28440223
http://dx.doi.org/10.7554/eLife.23043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404922/
https://www.ncbi.nlm.nih.gov/pubmed/28440223
http://dx.doi.org/10.7554/eLife.23043

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