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Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications
The nicotinic acetylcholine receptor (nAChR) is a major target of autoantibodies in myasthenia gravis (MG), an autoimmune disease that causes neuromuscular transmission dysfunction. Despite decades of research, the molecular mechanisms underlying MG have not been fully elucidated. Here, we present t...
Autores principales: | Noridomi, Kaori, Watanabe, Go, Hansen, Melissa N, Han, Gye Won, Chen, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404922/ https://www.ncbi.nlm.nih.gov/pubmed/28440223 http://dx.doi.org/10.7554/eLife.23043 |
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