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Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation

The cytosol-facing membranes of cellular organelles contain proteins that enable signal transduction, regulation of morphology and trafficking, protein import and export, and other specialized processes. Discovery of these proteins by traditional biochemical fractionation can be plagued with contami...

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Detalles Bibliográficos
Autores principales: Hung, Victoria, Lam, Stephanie S, Udeshi, Namrata D, Svinkina, Tanya, Guzman, Gaelen, Mootha, Vamsi K, Carr, Steven A, Ting, Alice Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404927/
https://www.ncbi.nlm.nih.gov/pubmed/28441135
http://dx.doi.org/10.7554/eLife.24463