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Dilation of fusion pores by crowding of SNARE proteins

Hormones and neurotransmitters are released through fluctuating exocytotic fusion pores that can flicker open and shut multiple times. Cargo release and vesicle recycling depend on the fate of the pore, which may reseal or dilate irreversibly. Pore nucleation requires zippering between vesicle-assoc...

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Detalles Bibliográficos
Autores principales: Wu, Zhenyong, Bello, Oscar D, Thiyagarajan, Sathish, Auclair, Sarah Marie, Vennekate, Wensi, Krishnakumar, Shyam S, O'Shaughnessy, Ben, Karatekin, Erdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404929/
https://www.ncbi.nlm.nih.gov/pubmed/28346138
http://dx.doi.org/10.7554/eLife.22964