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Alternative RNA splicing: contribution to pain and potential therapeutic strategy

Since the sequencing of metazoan genomes began, it has become clear that the number of expressed proteins far exceeds the number of genes. It is now estimated that more than 98% of human genes give rise to multiple proteins through alternative pre-mRNA splicing. In this review, we highlight the know...

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Detalles Bibliográficos
Autores principales: Donaldson, Lucy F., Beazley-Long, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405051/
https://www.ncbi.nlm.nih.gov/pubmed/27329269
http://dx.doi.org/10.1016/j.drudis.2016.06.017