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Alternative RNA splicing: contribution to pain and potential therapeutic strategy
Since the sequencing of metazoan genomes began, it has become clear that the number of expressed proteins far exceeds the number of genes. It is now estimated that more than 98% of human genes give rise to multiple proteins through alternative pre-mRNA splicing. In this review, we highlight the know...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405051/ https://www.ncbi.nlm.nih.gov/pubmed/27329269 http://dx.doi.org/10.1016/j.drudis.2016.06.017 |