Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery()

BACKGROUND: New vaccines to prevent tuberculosis are urgently needed. MVA85A is a novel viral vector TB vaccine candidate designed to boost BCG-induced immunity when delivered intradermally. To date, intramuscular delivery has not been evaluated. Skin and muscle have distinct anatomical and immunolo...

Descripción completa

Detalles Bibliográficos
Autores principales: Meyer, Joel, Harris, Stephanie A., Satti, Iman, Poulton, Ian D., Poyntz, Hazel C., Tanner, Rachel, Rowland, Rosalind, Griffiths, Kristin L., Fletcher, Helen A., McShane, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405058/
https://www.ncbi.nlm.nih.gov/pubmed/23266342
http://dx.doi.org/10.1016/j.vaccine.2012.12.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405058/
https://www.ncbi.nlm.nih.gov/pubmed/23266342
http://dx.doi.org/10.1016/j.vaccine.2012.12.042

Ejemplares similares