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Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery()
BACKGROUND: New vaccines to prevent tuberculosis are urgently needed. MVA85A is a novel viral vector TB vaccine candidate designed to boost BCG-induced immunity when delivered intradermally. To date, intramuscular delivery has not been evaluated. Skin and muscle have distinct anatomical and immunolo...
Autores principales: | Meyer, Joel, Harris, Stephanie A., Satti, Iman, Poulton, Ian D., Poyntz, Hazel C., Tanner, Rachel, Rowland, Rosalind, Griffiths, Kristin L., Fletcher, Helen A., McShane, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405058/ https://www.ncbi.nlm.nih.gov/pubmed/23266342 http://dx.doi.org/10.1016/j.vaccine.2012.12.042 |
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