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Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures

Botulinum neurotoxin type A (BoNT/A) and minocycline are potent drugs used in clinical therapies. The primary molecular mechanism of BoNT/A is the cleavage of SNARE proteins, which prevents cells from releasing neurotransmitters from vesicles, while the effects of minocycline are related to the inhi...

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Detalles Bibliográficos
Autores principales: Piotrowska, Anna, Popiolek-Barczyk, Katarzyna, Pavone, Flaminia, Mika, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405066/
https://www.ncbi.nlm.nih.gov/pubmed/28491822
http://dx.doi.org/10.3389/fcimb.2017.00141