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Sleep Disturbances in Phenylketonuria: An Explorative Study in Men and Mice

Sleep problems have not been directly reported in phenylketonuria (PKU). In PKU, the metabolic pathway of phenylalanine is disrupted, which, among others, causes deficits in the neurotransmitters and sleep modulators dopamine, norepinephrine, and serotonin. Understanding sleep problems in PKU patien...

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Detalles Bibliográficos
Autores principales: Bruinenberg, Vibeke M., Gordijn, Marijke C. M., MacDonald, Anita, van Spronsen, Francjan J., Van der Zee, Eddy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405067/
https://www.ncbi.nlm.nih.gov/pubmed/28491049
http://dx.doi.org/10.3389/fneur.2017.00167