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Sleep Disturbances in Phenylketonuria: An Explorative Study in Men and Mice
Sleep problems have not been directly reported in phenylketonuria (PKU). In PKU, the metabolic pathway of phenylalanine is disrupted, which, among others, causes deficits in the neurotransmitters and sleep modulators dopamine, norepinephrine, and serotonin. Understanding sleep problems in PKU patien...
Autores principales: | Bruinenberg, Vibeke M., Gordijn, Marijke C. M., MacDonald, Anita, van Spronsen, Francjan J., Van der Zee, Eddy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405067/ https://www.ncbi.nlm.nih.gov/pubmed/28491049 http://dx.doi.org/10.3389/fneur.2017.00167 |
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