Receptor-Mediated Melanoma Targeting with Radiolabeled α-Melanocyte-Stimulating Hormone: Relevance of the Net Charge of the Ligand

A majority of melanotic and amelanotic melanomas overexpress melanocortin type 1 receptors (MC1Rs) for α-melanocyte-stimulating hormone. Radiolabeled linear or cyclic analogs of α-MSH have a great potential as diagnostic or therapeutic tools for the management of malignant melanoma. Compounds such a...

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Detalles Bibliográficos
Autores principales: Bapst, Jean-Philippe, Eberle, Alex N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405074/
https://www.ncbi.nlm.nih.gov/pubmed/28491052
http://dx.doi.org/10.3389/fendo.2017.00093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405074/
https://www.ncbi.nlm.nih.gov/pubmed/28491052
http://dx.doi.org/10.3389/fendo.2017.00093

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