Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest

During mitosis, cells must segregate the replicated copies of their genome to their daughter cells with extremely high fidelity. Segregation errors lead to an abnormal chromosome number (aneuploidy), which typically results in disease or cell death [1]. Chromosome segregation and anaphase onset are...

Descripción completa

Detalles Bibliográficos
Autores principales: May, Karen M., Paldi, Flora, Hardwick, Kevin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405113/
https://www.ncbi.nlm.nih.gov/pubmed/28366744
http://dx.doi.org/10.1016/j.cub.2017.03.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405113/
https://www.ncbi.nlm.nih.gov/pubmed/28366744
http://dx.doi.org/10.1016/j.cub.2017.03.013

Ejemplares similares