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Multiple Myeloma Tumor Cells are Selectively Killed by Pharmacologically-dosed Ascorbic Acid

High-dose chemotherapies to treat multiple myeloma (MM) can be life-threatening due to toxicities to normal cells and there is a need to target only tumor cells and/or lower standard drug dosage without losing efficacy. We show that pharmacologically-dosed ascorbic acid (PAA), in the presence of iro...

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Detalles Bibliográficos
Autores principales: Xia, Jiliang, Xu, Hongwei, Zhang, Xiaoyan, Allamargot, Chantal, Coleman, Kristen L., Nessler, Randy, Frech, Ivana, Tricot, Guido, Zhan, Fenghuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405162/
https://www.ncbi.nlm.nih.gov/pubmed/28229908
http://dx.doi.org/10.1016/j.ebiom.2017.02.011