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Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways

Mitogen-activated protein kinases (MAPKs) and AMP­activated protein kinase α (AMPKα) play critical roles in the process of cardiac hypertrophy. Previous studies have demonstrated that piperine activates AMPKα and reduces the phosphorylation of extracellular signal-regulated kinase (ERK). However, th...

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Detalles Bibliográficos
Autores principales: Ma, Zhen-Guo, Yuan, Yu-Pei, Zhang, Xin, Xu, Si-Chi, Wang, Sha-Sha, Tang, Qi-Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405163/
https://www.ncbi.nlm.nih.gov/pubmed/28330809
http://dx.doi.org/10.1016/j.ebiom.2017.03.021