Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding Inhibitors

Nuclear factor of activated T cells 5 (NFAT5) has been implicated in the pathogenesis of various human diseases, including cancer and arthritis. However, therapeutic agents inhibiting NFAT5 activity are currently unavailable. To discover NFAT5 inhibitors, a library of > 40,000 chemicals was scree...

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Detalles Bibliográficos
Autores principales: Han, Eun-Jin, Kim, Hyun Young, Lee, Naeun, Kim, Nam-Hoon, Yoo, Seung-Ah, Kwon, H. Moo, Jue, Dae-Myung, Park, Yune-Jung, Cho, Chul-Soo, De, Tran Quang, Jeong, Dae Young, Lim, Hee-Jong, Park, Woo Kyu, Lee, Ge Hyeong, Cho, Heeyeong, Kim, Wan-Uk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405180/
https://www.ncbi.nlm.nih.gov/pubmed/28396011
http://dx.doi.org/10.1016/j.ebiom.2017.03.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405180/
https://www.ncbi.nlm.nih.gov/pubmed/28396011
http://dx.doi.org/10.1016/j.ebiom.2017.03.039

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