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Batf3-dependent CD8α(+) Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages

Dendritic cells (DCs) play an important role in controlling T cell-mediated adaptive immunity in atherogenesis. However, the role of the basic leucine zipper transcription factor, ATF-like 3 (Batf3)-dependent CD8α(+) DC subset in atherogenesis remains unclear. Here we show that Batf3(−/−) Apoe(−/−)...

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Detalles Bibliográficos
Autores principales: Li, Yalin, Liu, Xueyan, Duan, Wei, Tian, Hua, Zhu, Guangming, He, Hao, Yao, Shutong, Yi, Shuying, Song, Wengang, Tang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405198/
https://www.ncbi.nlm.nih.gov/pubmed/28411140
http://dx.doi.org/10.1016/j.ebiom.2017.04.008