Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity

Trehalose biosynthesis is found in fungi but not humans. Proteins involved in trehalose biosynthesis are essential for fungal pathogen virulence in humans and plants through multiple mechanisms. Loss of canonical trehalose biosynthesis genes in the human pathogen Aspergillus fumigatus significantly...

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Detalles Bibliográficos
Autores principales: Thammahong, Arsa, Caffrey-Card, Alayna K., Dhingra, Sourabh, Obar, Joshua J., Cramer, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405227/
https://www.ncbi.nlm.nih.gov/pubmed/28442603
http://dx.doi.org/10.1128/mBio.00056-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405227/
https://www.ncbi.nlm.nih.gov/pubmed/28442603
http://dx.doi.org/10.1128/mBio.00056-17

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