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An optimal stratified Simon two‐stage design

In Phase II oncology trials, therapies are increasingly being evaluated for their effectiveness in specific populations of interest. Such targeted trials require designs that allow for stratification based on the participants' molecular characterisation. A targeted design proposed by Jones and...

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Detalles Bibliográficos
Autores principales: Parashar, Deepak, Bowden, Jack, Starr, Colin, Wernisch, Lorenz, Mander, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405342/
https://www.ncbi.nlm.nih.gov/pubmed/26932771
http://dx.doi.org/10.1002/pst.1742