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Mild MPP(+) exposure-induced glucose starvation enhances autophagosome synthesis and impairs its degradation
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder, mainly characterised by the progressive loss of dopaminergic neurons. MPP(+) has been widely used as a PD-related neurotoxin, and their reports suggested the several hypotheses for neuronal cell death. However, most of these hypothe...
Autores principales: | Sakamoto, Shuichiro, Miyara, Masatsugu, Sanoh, Seigo, Ohta, Shigeru, Kotake, Yaichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405408/ https://www.ncbi.nlm.nih.gov/pubmed/28443637 http://dx.doi.org/10.1038/srep46668 |
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