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Improving preimplantation genetic diagnosis (PGD) reliability by selection of sperm donor with the most informative haplotype
BACKGROUND: The study is aimed to describe a novel strategy that increases the accuracy and reliability of PGD in patients using sperm donation by pre-selecting the donor whose haplotype does not overlap the carrier’s one. METHODS: A panel of 4–9 informative polymorphic markers, flanking the mutatio...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405512/ https://www.ncbi.nlm.nih.gov/pubmed/28446182 http://dx.doi.org/10.1186/s12958-017-0247-4 |