Circulating unmethylated insulin DNA as a potential non-invasive biomarker of beta cell death in type 1 Diabetes: a review and future prospect

BACKGROUND: The early detection of type 1 diabetes (T1D) largely depends on a reliable approach to monitor β cell loss. An effective way to evaluate the decline of β cell mass would allow early preventative intervention to preserve insulin secretion. MAIN BODY: Recent progress in the development of...

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Detalles Bibliográficos
Autores principales: Zhang, Kuo, Lin, Guigao, Han, Yanxi, Xie, Jiehong, Li, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405546/
https://www.ncbi.nlm.nih.gov/pubmed/28450972
http://dx.doi.org/10.1186/s13148-017-0343-5