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A scalable metabolite supplementation strategy against antibiotic resistant pathogen Chromobacterium violaceum induced by NAD(+)/NADH(+) imbalance

BACKGROUND: The leading edge of the global problem of antibiotic resistance necessitates novel therapeutic strategies. This study develops a novel systems biology driven approach for killing antibiotic resistant pathogens using benign metabolites. RESULTS: Controlled laboratory evolutions establishe...

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Detalles Bibliográficos
Autores principales: Banerjee, Deepanwita, Parmar, Dharmeshkumar, Bhattacharya, Nivedita, Ghanate, Avinash D., Panchagnula, Venkateswarlu, Raghunathan, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405553/
https://www.ncbi.nlm.nih.gov/pubmed/28446174
http://dx.doi.org/10.1186/s12918-017-0427-z