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Prospects and limitations of antibody-mediated clearing of lipoproteins from blood plasma prior to nanoparticle tracking analysis of extracellular vesicles

Introduction: Nanoparticle tracking analysis (NTA) enables measurement of extracellular vesicles (EVs) but lacks the ability to distinct between EVs and lipoproteins which are abundantly present in blood plasma. Limitations in ultracentrifugation and size exclusion chromatography applied for EV isol...

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Detalles Bibliográficos
Autores principales: Mørk, Morten, Handberg, Aase, Pedersen, Shona, Jørgensen, Malene M., Bæk, Rikke, Nielsen, Morten K., Kristensen, Søren R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405563/
https://www.ncbi.nlm.nih.gov/pubmed/28473885
http://dx.doi.org/10.1080/20013078.2017.1308779