Commentary: A Myriad Aberrations on Information of Ontogeny of Drug Metabolizing Enzymes in the Pediatric Population: An Obstacle for Personalizing Drug Therapy in the Pediatric Population

Major lacunae exist in our understanding of how developmental changes in drug biotransformation influence drug’s exposure and thus its efficacy and toxicity in children. It is not just about smaller weight in children, which modifies the pattern of the drug's exposure. There are developmental,...

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Detalles Bibliográficos
Autores principales: Uppugunduri, Chakradhara Rao S., Ansari, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405624/
https://www.ncbi.nlm.nih.gov/pubmed/26908134
http://dx.doi.org/10.2174/1872312810666160224143443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405624/
https://www.ncbi.nlm.nih.gov/pubmed/26908134
http://dx.doi.org/10.2174/1872312810666160224143443

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