Impaired intracortical inhibition demonstrated in vivo in people with Dravet syndrome

OBJECTIVE: Dravet syndrome is a rare neurodevelopmental disorder characterized by seizures and other neurologic problems. SCN1A mutations account for ∼80% of cases. Animal studies have implicated mutation-related dysregulated cortical inhibitory networks in its pathophysiology. We investigated such...

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Detalles Bibliográficos
Autores principales: Stern, William M., Sander, Josemir W., Rothwell, John C., Sisodiya, Sanjay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405762/
https://www.ncbi.nlm.nih.gov/pubmed/28356460
http://dx.doi.org/10.1212/WNL.0000000000003868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405762/
https://www.ncbi.nlm.nih.gov/pubmed/28356460
http://dx.doi.org/10.1212/WNL.0000000000003868

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