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Newly Formed Reticulated Platelets Undermine Pharmacokinetically Short-Lived Antiplatelet Therapies

OBJECTIVE—: Aspirin together with thienopyridine P2Y(12) inhibitors, commonly clopidogrel, is a cornerstone of antiplatelet therapy. However, many patients receiving this therapy display high on-treatment platelet reactivity, which is a major therapeutic hurdle to the prevention of recurrent thrombo...

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Detalles Bibliográficos
Autores principales: Armstrong, Paul C., Hoefer, Thomas, Knowles, Rebecca B., Tucker, Arthur T., Hayman, Melissa A., Ferreira, Plinio M., Chan, Melissa V., Warner, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405774/
https://www.ncbi.nlm.nih.gov/pubmed/28279968
http://dx.doi.org/10.1161/ATVBAHA.116.308763