Insulin Growth Factor 1 Protects Neural Stem Cells Against Apoptosis Induced by Hypoxia Through Akt/Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase (Akt/MAPK/ERK) Pathway in Hypoxia-Ishchemic Encephalopathy

BACKGROUND: Insulin growth factor 1 (IGF-1) is reported to modulate cell growth and acts as potential therapy for traumatic brain injury. This study was designed to investigate the effect of IGF-1 on hypoxia-induced apoptosis in neural stem cells (NSCs). MATERIAL/METHODS: A hypoxia model was constru...

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Detalles Bibliográficos
Autores principales: Zhao, Bing, Zheng, Zebao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405785/
https://www.ncbi.nlm.nih.gov/pubmed/28420864
http://dx.doi.org/10.12659/MSM.901055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405785/
https://www.ncbi.nlm.nih.gov/pubmed/28420864
http://dx.doi.org/10.12659/MSM.901055

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