Chemical synthesis of RNA with site-specific methylphosphonate modifications

Methylphosphonate(mP)-modified RNA serves as valuable probe to evaluate biomolecular interactions between the nucleic acid backbone and binding partners, such as proteins or small molecules. Here, we describe an efficient workflow for the synthesis of RNA with a single mP modification in diastereome...

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Detalles Bibliográficos
Autores principales: Flür, Sara, Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405801/
https://www.ncbi.nlm.nih.gov/pubmed/27037236
http://dx.doi.org/10.1016/j.ymeth.2016.03.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405801/
https://www.ncbi.nlm.nih.gov/pubmed/27037236
http://dx.doi.org/10.1016/j.ymeth.2016.03.024

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