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A structural ensemble of a ribosome-nascent chain complex during co-translational protein folding

While detailed pictures are emerging of the structures of ribosomes, little is known at the atomic level about the structural and co-translational folding properties of nascent polypeptide chains. Here we have used solution-state NMR spectroscopy to define a structural ensemble of a ribosome-nascent...

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Detalles Bibliográficos
Autores principales: Cabrita, Lisa D., Cassaignau, AnaÏs M.E., Launay, Helene M.M., Waudby, Christopher A., Wlodarski, Tomasz, Camilloni, Carlo, Karyadi, Maria-Evangelia, Robertson, Amy L., Wang, Xiaolin, Wentink, Anne S., Goodsell, Luke, Woolhead, Cheryl A., Vendruscolo, Michele, Dobson, Christopher M., Christodoulou, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405865/
https://www.ncbi.nlm.nih.gov/pubmed/26926436
http://dx.doi.org/10.1038/nsmb.3182