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Tryptase mast cell density, protease-activated receptor-2 microvascular density, and classical microvascular density evaluation in gastric cancer patients undergoing surgery: possible translational relevance

BACKGROUND: Mast cells (MCs) can stimulate angiogenesis, releasing several proangiogenic cytokines stored in their cytoplasm. In particular, MCs can release tryptase, a potent in vivo and in vitro proangiogenic factor via protease-activated receptor-2 (PAR-2) activation and mitogen-activated protein...

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Detalles Bibliográficos
Autores principales: Ammendola, Michele, Sacco, Rosario, Vescio, Giuseppina, Zuccalà, Valeria, Luposella, Maria, Patruno, Rosa, Zizzo, Nicola, Gadaleta, Claudia, Marech, Ilaria, Ruggieri, Roberta, Kocak, Ibrahim Furkan, Ozgurtas, Taner, Gadaleta, Cosmo Damiano, Sammarco, Giuseppe, Ranieri, Girolamo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405880/
https://www.ncbi.nlm.nih.gov/pubmed/28491140
http://dx.doi.org/10.1177/1756283X16673981