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AntagomiR-451 inhibits oxygen glucose deprivation (OGD)-induced HUVEC necrosis via activating AMPK signaling

Oxygen glucose deprivation (OGD) application in cultured human umbilical vein endothelial cells (HUVECs) mimics ischemic injuries. AntagomiR-451, the miroRNA-451 (“miR-451”) inhibitor, could activate pro-survival AMP-activated protein kinase (AMPK) signaling. In the current study, we showed that for...

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Detalles Bibliográficos
Autores principales: Yang, Xi, He, Xiao-Qing, Li, Guo-Dong, Xu, Yong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405932/
https://www.ncbi.nlm.nih.gov/pubmed/28445531
http://dx.doi.org/10.1371/journal.pone.0175507