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Proportions of circulating follicular helper T cells are reduced and correlate with memory B cells in HIV-infected children

INTRODUCTION: HIV causes defects in memory B cells in children, but the mechanisms of those defects have not been fully elucidated. One possible mechanism is the lack of T-cell help to B cells during immune reactions. However, few studies have assessed the effect of HIV on follicular helper T cells...

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Detalles Bibliográficos
Autores principales: Muema, Daniel M., Macharia, Gladys N., Olusola, Babatunde A., Hassan, Amin S., Fegan, Greg W., Berkley, James A., Urban, Britta C., Nduati, Eunice W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405965/
https://www.ncbi.nlm.nih.gov/pubmed/28445512
http://dx.doi.org/10.1371/journal.pone.0175570