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Baicalein protects rat insulinoma INS-1 cells from palmitate-induced lipotoxicity by inducing HO-1

OBJECTIVE: β-Cell dysfunction plays a central role in the pathogenesis of type 2 diabetes (T2D), and the identification of novel approaches to improve β-cell function is essential to treat this disease. Baicalein, a flavonoid originally isolated from the root of Scutellaria Baicalensis, has been sho...

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Detalles Bibliográficos
Autores principales: Kwak, Hyun Jeong, Yang, Dongki, Hwang, Yongha, Jun, Hee-Sook, Cheon, Hyae Gyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405981/
https://www.ncbi.nlm.nih.gov/pubmed/28445528
http://dx.doi.org/10.1371/journal.pone.0176432