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Impact of the c-Myb(E308G) mutation on mouse myelopoiesis and dendritic cell development

Booreana mice carrying the c-Myb(308G) point mutation were analyzed to determine changes in early hematopoiesis in the bone marrow and among mature cells in the periphery. This point mutation led to increased numbers of early hematopoietic stem and progenitor cells (HSPCs), with a subsequent reducti...

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Detalles Bibliográficos
Autores principales: Papathanasiou, Peter, Petvises, Sawang, Hey, Ying-Ying, Perkins, Andrew C., O’Neill, Helen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405991/
https://www.ncbi.nlm.nih.gov/pubmed/28445549
http://dx.doi.org/10.1371/journal.pone.0176345