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IQGAP1 is an oncogenic target in canine melanoma

Canine oral mucosal melanoma is an aggressive malignant neoplasm and is characterized by local infiltration and a high metastatic potential. The disease progression is similar to that of human oral melanomas. Whereas human cutaneous melanoma is primarily driven by activating mutations in Braf (60%)...

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Detalles Bibliográficos
Autores principales: Lee, Becky H., Neela, Poornima H., Kent, Michael S., Zehnder, Ashley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406000/
https://www.ncbi.nlm.nih.gov/pubmed/28445541
http://dx.doi.org/10.1371/journal.pone.0176370