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IQGAP1 is an oncogenic target in canine melanoma
Canine oral mucosal melanoma is an aggressive malignant neoplasm and is characterized by local infiltration and a high metastatic potential. The disease progression is similar to that of human oral melanomas. Whereas human cutaneous melanoma is primarily driven by activating mutations in Braf (60%)...
Autores principales: | Lee, Becky H., Neela, Poornima H., Kent, Michael S., Zehnder, Ashley M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406000/ https://www.ncbi.nlm.nih.gov/pubmed/28445541 http://dx.doi.org/10.1371/journal.pone.0176370 |
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