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Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres

Cancer cells rely on the activation of telomerase or the alternative lengthening of telomeres (ALT) pathways for telomere maintenance and survival. ALT involves homologous recombination (HR)-dependent exchange and/or HR-associated synthesis of telomeric DNA. Utilizing proximity-dependent biotinylati...

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Detalles Bibliográficos
Autores principales: Garcia-Exposito, Laura, Bournique, Elodie, Bergoglio, Valérie, Bose, Arindam, Barroso-Gonzalez, Jonathan, Zhang, Sufang, Roncaioli, Justin L., Lee, Marietta, Wallace, Callen T., Watkins, Simon C., Opresko, Patricia L., Hoffmann, Jean-Sébastien, O’Sullivan, Roderick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406014/
https://www.ncbi.nlm.nih.gov/pubmed/27829156
http://dx.doi.org/10.1016/j.celrep.2016.10.048