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Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres
Cancer cells rely on the activation of telomerase or the alternative lengthening of telomeres (ALT) pathways for telomere maintenance and survival. ALT involves homologous recombination (HR)-dependent exchange and/or HR-associated synthesis of telomeric DNA. Utilizing proximity-dependent biotinylati...
Autores principales: | Garcia-Exposito, Laura, Bournique, Elodie, Bergoglio, Valérie, Bose, Arindam, Barroso-Gonzalez, Jonathan, Zhang, Sufang, Roncaioli, Justin L., Lee, Marietta, Wallace, Callen T., Watkins, Simon C., Opresko, Patricia L., Hoffmann, Jean-Sébastien, O’Sullivan, Roderick J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406014/ https://www.ncbi.nlm.nih.gov/pubmed/27829156 http://dx.doi.org/10.1016/j.celrep.2016.10.048 |
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