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TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection
Establishing functional tissue-resident memory (T(RM)) cells at sites of infection is a newfound objective of T cell vaccine design. To directly assess the impact of antigen stimulation strength on memory CD8 T cell formation and function during a persistent viral infection, we created a library of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406018/ https://www.ncbi.nlm.nih.gov/pubmed/28410427 http://dx.doi.org/10.1371/journal.ppat.1006318 |