Cargando…
TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection
Establishing functional tissue-resident memory (T(RM)) cells at sites of infection is a newfound objective of T cell vaccine design. To directly assess the impact of antigen stimulation strength on memory CD8 T cell formation and function during a persistent viral infection, we created a library of...
Autores principales: | Maru, Saumya, Jin, Ge, Schell, Todd D., Lukacher, Aron E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406018/ https://www.ncbi.nlm.nih.gov/pubmed/28410427 http://dx.doi.org/10.1371/journal.ppat.1006318 |
Ejemplares similares
-
IL-21 in Homeostasis of Resident Memory and Exhausted CD8 T Cells during Persistent Infection
por: Ren, Heather M., et al.
Publicado: (2020) -
PD-1 Dynamically Regulates Inflammation and Development of Brain-Resident Memory CD8 T Cells During Persistent Viral Encephalitis
por: Shwetank,, et al.
Publicado: (2019) -
To Go or Stay: The Development, Benefit, and Detriment of Tissue-Resident Memory CD8 T Cells during Central Nervous System Viral Infections
por: Mockus, Taryn E., et al.
Publicado: (2019) -
Inhibition of Retrograde Transport Limits Polyomavirus Infection In Vivo
por: Maru, Saumya, et al.
Publicado: (2017) -
Whole body irradiation and agonist anti-CD40 synergize to promote adoptive T cell therapy of resistant murine pancreatic neuroendocrine tumors
por: Ward-Kavanagh, Lindsay, et al.
Publicado: (2015)