Cargando…

Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9

Bacterial biofilms are associated with numerous human infections. The predominant protein expressed in enteric biofilms is the amyloid curli, which forms highly immunogenic complexes with DNA. Infection with curli-expressing bacteria or systemic exposure to purified curli-DNA complexes triggers auto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tursi, Sarah A., Lee, Ernest Y., Medeiros, Nicole J., Lee, Michael H., Nicastro, Lauren K., Buttaro, Bettina, Gallucci, Stefania, Wilson, Ronald Paul, Wong, Gerard C. L., Tükel, Çagla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406031/ https://www.ncbi.nlm.nih.gov/pubmed/28410407 http://dx.doi.org/10.1371/journal.ppat.1006315

Ejemplares similares

Salmonella Typhimurium biofilm disruption by a human antibody that binds a pan-amyloid epitope on curli
por: Tursi, Sarah A., et al.
Publicado: (2020)

The Functional Amyloid Curli Protects Escherichia coli against Complement-Mediated Bactericidal Activity
por: Biesecker, Steven G., et al.
Publicado: (2018)

Assembly of ordered DNA-curli fibril complexes during Salmonella biofilm formation correlates with strengths of the type I interferon and autoimmune responses
por: Nicastro, Lauren K., et al.
Publicado: (2022)

Development of a New Bead Movement-Based Computational Framework Shows that Bacterial Amyloid Curli Reduces Bead Mobility in Biofilms
por: Malhotra, K., et al.
Publicado: (2020)

Nitrate Is an Environmental Cue in the Gut for Salmonella enterica Serovar Typhimurium Biofilm Dispersal through Curli Repression and Flagellum Activation via Cyclic-di-GMP Signaling
por: Miller, Amanda L., et al.
Publicado: (2022)

In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection
por: Miller, Amanda L., et al.
Publicado: (2020)

Phenol-Soluble Modulins From Staphylococcus aureus Biofilms Form Complexes With DNA to Drive Autoimmunity
por: Grando, Kaitlyn, et al.
Publicado: (2022)

Systemic exposure to bacterial amyloid curli alters the gut mucosal immune response and the microbiome, exacerbating Salmonella-induced arthritis
por: Bessho, Shingo, et al.
Publicado: (2023)

Amyloid-containing biofilms and autoimmunity
por: Miller, Amanda L., et al.
Publicado: (2022)

Biofilm-associated bacterial amyloids dampen inflammation in the gut: oral treatment with curli fibres reduces the severity of hapten-induced colitis in mice
por: Oppong, Gertrude O, et al.
Publicado: (2015)

Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation
por: Lee, Ernest Y., et al.
Publicado: (2020)

Disease to Dirt: The Biology of Microbial Amyloids
por: Hufnagel, David A., et al.
Publicado: (2013)

Congo Red Interactions with Curli-Producing E. coli and Native Curli Amyloid Fibers
por: Reichhardt, Courtney, et al.
Publicado: (2015)

Selective constraint acting on TLR2 and TLR4 genes of Japanese Rana frogs
por: Lau, Quintin, et al.
Publicado: (2018)

Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis
por: Kim, Geun-Tae, et al.
Publicado: (2009)

Structural analysis and architectural principles of the bacterial amyloid curli
por: Sleutel, Mike, et al.
Publicado: (2023)

Microbiome or Infections: Amyloid-Containing Biofilms as a Trigger for Complex Human Diseases
por: Miller, Amanda L., et al.
Publicado: (2021)

Curly Encodes Dual Oxidase, Which Acts with Heme Peroxidase Curly Su to Shape the Adult Drosophila Wing
por: Hurd, Thomas Ryan, et al.
Publicado: (2015)

The Bacterial Amyloid Curli Is Associated with Urinary Source Bloodstream Infection
por: Hung, Chia, et al.
Publicado: (2014)

The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6
por: Irvine, Katherine Lucy, et al.
Publicado: (2013)

Correction: Curly Encodes Dual Oxidase, Which Acts with Heme Peroxidase Curly Su to Shape the Adult Drosophila Wing
por: Hurd, Thomas Ryan, et al.
Publicado: (2016)

TLR7 and IgM: Dangerous Partners in Autoimmunity
por: Amendt, Timm, et al.
Publicado: (2023)

The nonsense allele oblivious reveals a sensor of di-acylglycerides acting in conjunction with TLR2 and TLR6
por: Hoebe, K, et al.
Publicado: (2004)

Potential value of pharmacological agents acting on toll-like receptor (TLR) 7 and/or TLR8 in COVID-19
por: Khalifa, Amani E., et al.
Publicado: (2021)

The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis
por: Roshan, Mohsin H. K., et al.
Publicado: (2016)

NMR insights into the pre-amyloid ensemble and secretion targeting of the curli subunit CsgA
por: Sewell, Lee, et al.
Publicado: (2020)

A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1
por: Wang, XiaoYan, et al.
Publicado: (2021)

The Production of Curli Amyloid Fibers Is Deeply Integrated into the Biology of Escherichia coli
por: Smith, Daniel R., et al.
Publicado: (2017)

The Processed Amino-Terminal Fragment of Human TLR7 Acts as a Chaperone To Direct Human TLR7 into Endosomes
por: Hipp, Madeleine M., et al.
Publicado: (2015)

rCUR: an R package for CUR matrix decomposition
por: Bodor, András, et al.
Publicado: (2012)

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9
por: Guiducci, Cristiana, et al.
Publicado: (2010)

Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses
por: Meng, Jonathan X., et al.
Publicado: (2022)

STRAP Acts as a Scaffolding Protein in Controlling the TLR2/4 Signaling Pathway
por: Huh, Hyunbin D., et al.
Publicado: (2016)

IL-4 Suppresses the Responses to TLR7 and TLR9 Stimulation and Increases the Permissiveness to Retroviral Infection of Murine Conventional Dendritic Cells
por: Sriram, Uma, et al.
Publicado: (2014)

Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis
por: González-Reyes, Salomé, et al.
Publicado: (2010)

Central Nervous System-Endogenous TLR7 and TLR9 Induce Different Immune Responses and Effects on Experimental Autoimmune Encephalomyelitis
por: Dieu, Ruthe Storgaard, et al.
Publicado: (2021)

Screening of herbal extracts for TLR2- and TLR4-dependent anti-inflammatory effects
por: Schink, Anne, et al.
Publicado: (2018)

Elicited soybean extract attenuates proinflammatory cytokines expression by modulating TLR3/TLR4 activation in high−fat, high−fructose diet mice
por: Atho’illah, Mochammad Fitri, et al.
Publicado: (2021)

TLR2 and TLR4 in Ischemia Reperfusion Injury
por: Arslan, F., et al.
Publicado: (2010)

Resveratrol attenuates TLR-4 mediated inflammation and elicits therapeutic potential in models of sepsis
por: Wang, Binbin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fo48fhd82fc4gk039ro0db280q