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Crosstalk and the Dynamical Modularity of Feed-Forward Loops in Transcriptional Regulatory Networks

Network motifs, such as the feed-forward loop (FFL), introduce a range of complex behaviors to transcriptional regulatory networks, yet such properties are typically determined from their isolated study. We characterize the effects of crosstalk on FFL dynamics by modeling the cross regulation betwee...

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Detalles Bibliográficos
Autores principales: Rowland, Michael A., Abdelzaher, Ahmed, Ghosh, Preetam, Mayo, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406374/
https://www.ncbi.nlm.nih.gov/pubmed/28445746
http://dx.doi.org/10.1016/j.bpj.2017.02.044