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Germline and somatic genetic changes in multicentric tumors obtained from a patient with multiple endocrine neoplasia type 1

Multiple endocrine neoplasia type 1 (MEN1) is a hereditary cancer syndrome caused by germline mutations of the MEN1 gene located in chromosome 11q13. In patients with MEN1, multicentric tumors develop in the involved organs; however, precise evaluation of genetic changes in these multicentric tumors...

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Detalles Bibliográficos
Autores principales: Naruoka, Akane, Ohnami, Sumiko, Nagashima, Takeshi, Serizawa, Masakuni, Ohshima, Keiichi, Ohnami, Shumpei, Urakami, Kenichi, Horiuchi, Yasue, Kiyozumi, Yoshimi, Abe, Masato, Nakajima, Takashi, Sugiura, Teiichi, Uesaka, Katsuhiko, Kusuhara, Masatoshi, Yamaguchi, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406389/
https://www.ncbi.nlm.nih.gov/pubmed/28503312
http://dx.doi.org/10.1038/hgv.2017.13