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Germline and somatic genetic changes in multicentric tumors obtained from a patient with multiple endocrine neoplasia type 1
Multiple endocrine neoplasia type 1 (MEN1) is a hereditary cancer syndrome caused by germline mutations of the MEN1 gene located in chromosome 11q13. In patients with MEN1, multicentric tumors develop in the involved organs; however, precise evaluation of genetic changes in these multicentric tumors...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406389/ https://www.ncbi.nlm.nih.gov/pubmed/28503312 http://dx.doi.org/10.1038/hgv.2017.13 |