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Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology

Leptospira spp. are diderm (two membranes) bacteria that infect mammals causing leptospirosis, a public health problem with global implications. Thousands of people die every year due to leptospirosis, especially in developing countries with tropical climates. Prophylaxis is difficult due to multipl...

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Detalles Bibliográficos
Autores principales: Grassmann, André Alex, Kremer, Frederico Schmitt, dos Santos, Júlia Cougo, Souza, Jéssica Dias, Pinto, Luciano da Silva, McBride, Alan John Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406399/
https://www.ncbi.nlm.nih.gov/pubmed/28496441
http://dx.doi.org/10.3389/fimmu.2017.00463